Biofluids
Biofluids are liquids originating from inside the bodies of living people. They include fluids that are excreted or secreted from the body as well as body water that normally is not.
State of the art Computational Fluid Dynamics tools coupled with real life experimentations increase our understanding of biofluids related problems. A close collaboration between scientists/researchers and the medical community can help to better understand disease initiation, progression and diagnosis through the prediction and analysis of fluid motion within the human body.
Typical biofluids related problems are listed below:
- pulsatile flow through a blood vessel with an intracranial aneurysm,
- carotid bifurcation that exhibits a severely stenosed internal branch,
- blood flow past prosthetic heart valves,
- fluid structure interaction of a mechanical bileaflet heart valve in an straight aorta at physiologic pulsatile conditions,
- development and testing of biomedical devices,
- drug delivery agents in human blood flow.
The increasing use of modern CFD tools will allow the medical community to better predict, suggest or evaluate new treatment modalities and surgical techniques for their patients.
Computational Fluid Dynamics Challenge
I participated in the CFD Challenge for rupture-prediction in intracranial aneurysms. The challenge involved two patient-specific MCA-aneurysms that were analyzed by CFD in a blind test. Phase I: Participants predicted which one was the ruptured aneurysm and at which location the rupture took place. They were free to choose their computational model, software and boundary conditions. Phase II: Participants will be asked to repeat their computational study with prescribed boundary conditions. It aims on checking the variability of the computational results among the different groups. The results of both phases were presented at the WFITN & ICS 2013 conference in Buenos Aires.
The paper "The Computational Fluid Dynamics Rupture Challenge 2013 - Phase I: Prediction of Rupture Status in Intracranial Aneurysms" is available. Phase II (submitted the Journal of Biomechanical Engineering) is still under review.
